Angelegte Studien

In über 22 groß angelegten Studien zu den Liadin Reizdarm Wirkstoffen konnte eine signifikante Verbesserung der Symptome eines Reizdarmsyndroms, eine Normalisierung der Darmflora und eine Förderung der richtigen Darmfunktion belegt werden.

  • 1
    Partially hydrolyzed guar gum: a fiber as coadjuvant in the irritable colon syndrome. PubMed 11382164 Giaccari S. et al.; Clin Ter. 152(1):21-5.; 2001
  • 2
    High-Fiber Supplementation in patients with Irritable Bowel Syndrome (IBS). A multicenter, open trial comparison between wheat bran diet and Partially Hydrolyzed Guar Gum (PHGG). PubMed; 12184518 Parisi G. et al.; Dig Dis Sci. 47(8):1697-1704.; 2002
  • 3
    Treatment effects of partially hydrolyzed guar gum on symptoms and quality of life of patients with irritable bowel syndrome. A multicenter randomized open trial. PubMed 15986863 Parisi G. et al.; Dig Dis Sci. 50(6):1107-12.; 2005
  • 4
    Therapeutic efficacy of partially hydrolysed rubber-guar fiber in the functional intestinal constipation of hospitalized patients. PubMed 18425236 Belo G.M. et al.; Arq Gastroenterol. 45(1):93-5.; 2008
  • 5
    Partially hydrolyzed guar gum in pediatric functional abdominal pain. PubMed 23345946 Romano C. et al. World J Gastroenterol. 19(2):235-40.; 2013
  • 6
    Partially hydrolyzed guar gum in the treatment of irritable bowel syndrome with constipation: effects of gender, age, and body mass index. PubMed 25843197 Russo L. et al. Saudi J Gastroenterol. 21(2):104-10.; 2015
  • 7
    Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients with irritable bowel syndrome. PubMed 26855665; Niv E. et al. Nutr Metab 13:10.; 2016
  • 8
    Scientific Opinion on the substantiation of health claims related to partially hydrolysed guar gum (PHGG) and decreasing potentially pathogenic gastro-intestinal microorganisms (ID 788), changes in short chain fatty acid (SCFA) production and/or pH in the gastro-intestinal tract (ID 787, 813), changes in bowel function (ID 813, 853, 1902, 1903, 1904, 2929, 2930, 2931), and reduction of gastrointestinal discomfort (ID 813, 1902, 1903, 1904, 2929, 2930, 2931) pursuant to Article 13(1) of Regulation (EC) No 1924/2006.; EFSA Journal 9(6):2254.; 2011
  • 9
    Irritable Bowel Syndrome: Clinical Manifestations, Dietary Influences, and Management. PubMed 28445436 Ikechi R. et al.; Healthcare 5(2):21.; 2017
  • 10
    Nonpharmacologic treatment of functional abdominal pain disorders: a systematic review. PubMed 25667239; Rutten J.M. et al. Pediatrics 135(3):522-35.; 2015
  • 11
    Gastrointestinal gas. PubMed 3058280 Fardy J. et al.; CMAJ. 139(12):1137.; 1988
  • 12
    Intestinal gas and functional disease of the digestive tract PubMed 12681122; Serra Pueyo J. Gastroenterol Hepatol. 26:263.; 2003
  • 13
    Intestinal gas dynamics: mechanisms and clinical relevance. PubMed 15951528; Azpiroz F. Gut 54:893; 2005
  • 14
    14 A trial of methylpolysiloxane in the treatment of abdominal distension. Marks I.N. et al.; S Afr Med J 39:476.; 1965
  • 15
    Activated charcoal, simethicone, and intestinal gas: a double-blind study. PubMed 3717809 Jain NK et al.; Ann Intern Med. 105(1):61.; 1986
  • 16
    Randomised double-blind comparison of simethicone with cisapride in functional dyspepsia. PubMed 10571602 Holtmann G. et al.; Aliment Pharmacol Ther. 13(11):1459.; 1999
  • 17
    A randomized placebo-controlled trial of simethicone and cisapride for the treatment of patients with functional dyspepsia. PubMed 11190223 Holtmann G. et al.; Aliment Pharmacol Ther. 16(9):1641.; 2002
  • 18
    Review of the Therapeutic Use of Simethicone in Gastroenterology. Meier R., Steuerwald M.; Schweiz. Zschr. Ganzheits Medizin 19(7/8):380; 2007
  • 19
    FPIN's Clinical Inquiries: Effective management of flatulence. Pubmed 19530642 Bailey J. et al.; Am Fam Physician. 79:1098.; 2009
  • 20
    Intestinal gas production and gastrointestinal symptoms: from pathogenesis to clinical implication. PubMed 24443061 Scaldaferri F. et al.; Eur Rev Med Pharmacol Sci. 17 Suppl 2:2.; 2013
  • 21
    Simethicone adjunct to polyethylene glycol improves small bowel capsule endoscopy imaging in non-Crohn’s disease patients. Pubmed 26423317 Papamichael K. et al; Ann Gastroenterol 28:464.; 2015
  • 22
    Comparison of new medical device and domperidone in patients with functional dyspepsia: randomized, cross-over, controlled trial. Gallo A. et al.; Minerva Med. 102(2):133-9.; 2011

Weitere Informationen

Liadin® unterstützt die Darmfunktion

Liadin® Reizdarm unterstützt die Darmfunktion, hilft dabei exogene und endogene Toxine, die das Darmnervensystem schädigen können, zu absorbieren. Es bindet bspw. überschüssige Gallensäure und unterstützt bei der Ausscheidung.

Beschwerden und Behandlung

Chronische Darmbeschwerden sind für die Betroffenen störend und oft eine lästige Qual. Die meisten Patienten leiden häufig unter Bauchschmerzen, Blähungen, Durchfall oder Verstopfung und kennen gar nicht den Grund dafür.

Mechanism

Volksleiden Reizdarm

15 Millionen Menschen leiden am Reizdarmsyndrom. Jeder zweite Arztbesuch wegen Magen-Darm-Beschwerden erhält mittlerweile diese Diagnose.